Prevalence of Asymptomatic Infection by <i>Treponema pallidum</i> in Pregnants of the Baixada Fluminense Region, Province of Rio de Janeiro, Brazil

Ana Carolina Torres; Antonio Neres Norberg; Fabiano Guerra Sanches; Jose Tadeu Madeira-Oliveira; Alex Nagem Machado; Paulo Cesar Ribeiro; Nicolau Maues Serra-Freire

doi:doi:10.11648/j.sjph.20160403.20

Prevalence of Asymptomatic Infection by Treponema pallidum in Pregnants of the Baixada Fluminense Region, Province of Rio de Janeiro, Brazil

Ana Carolina Torres, Antonio Neres Norberg, Fabiano Guerra Sanches, Jose Tadeu Madeira-Oliveira, Alex Nagem Machado, Paulo Cesar Ribeiro, Nicolau Maues Serra-Freire

Published in Science Journal of Public Health (Volume 4, Issue 3)

Received: 18 April 2016 Accepted: 27 April 2016 Published: 14 May 2016

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Abstract

Syphilis is an infectious disease with worldwide distribution caused by Treponema pallidum, and has great clinical importance when the pathogenesis is in pregnant women. The congenital disease is the result of the infection by vertical transmission of the Treponema to the fetus and can be the cause of high morbidity of the concepts during intrauterine life. It can also cause serious problems during pregnancy such as expontaneous abortus, premature babies with low weight, stillbournes, neonatal mortality, and early or late complications in children who survive to the infection. The aim of this study is to investigate the prevalence of syphilis in pregnants in obstetrics clinics in the Baixada Fluminense region and advise the seropositives for appropriate treatment and evaluate the intervention, contributing to the eradicate to the maternal diseases and preventing the transmission of the Treponema to the concepts. During the years 2010 and 2011, venous blood samples were collected from 1183 asymptomatic adult pregnants accompanied by obstetricians to detect anti-T. pallidum. The serum obtained from the blood was frozen and stored at -20°C until the analysis by serologic reactions of Venereal Disease Research Laboratory (VDRL) and passive hemagglutination (TPHA). The results showed 28 cases were diagnosed with titers equal or superior to 1:16, suggestive of syphilitic disease, corresponding to the coefficient of prevalence of 2.37%. There were dominance of cases in pregnants in the etary group between 21 and 30 years old. There is asymptomatic infection among the examined pregnants of Baixada Fluminense region, with possible risk of vertical transmission of infection to their concepts.

Published in	Science Journal of Public Health (Volume 4, Issue 3)
DOI	10.11648/j.sjph.20160403.20
Page(s)	224-228
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2016. Published by Science Publishing Group

Keywords

Syphilis, Abortus, Stillborn, Drug Treatment (Source: MeSH: MeSH NLM)

References

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[4]	Tavares R, Gontijo EEL, Santos ES, Jubé JKB, Mazutti AR, Silva MG. Perfil de grávidas com sífilis, HIV+ ou hepatite B em Gurupi, Tocantins. Rev Saúde e Pesquisa 2014; 7(1): 35-45.
[5]	Porth CM, Matfing G. Fisiopatologia. Ed Guanabara Koogan, Rio de Janeiro, 2016, p. 1204-1206.
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[16]	Malakar M. Ocurrence of syphilis women of the Lakhimpur district of Assam, India. Intern J Adv Res Technol 2014; 3: 77-81.
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[18]	Rios-Gonzalez CM. Prevalencia de sifilis en embarazadas que acuden al control prenatal en un hospital, 2014. Rev Cienc Invest Est Med Latinoam 2015; 20(1): 1.
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APA Style

Ana Carolina Torres, Antonio Neres Norberg, Fabiano Guerra Sanches, Jose Tadeu Madeira-Oliveira, Alex Nagem Machado, et al. (2016). Prevalence of Asymptomatic Infection by Treponema pallidum in Pregnants of the Baixada Fluminense Region, Province of Rio de Janeiro, Brazil. Science Journal of Public Health, 4(3), 224-228. https://doi.org/10.11648/j.sjph.20160403.20

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ACS Style

Ana Carolina Torres; Antonio Neres Norberg; Fabiano Guerra Sanches; Jose Tadeu Madeira-Oliveira; Alex Nagem Machado, et al. Prevalence of Asymptomatic Infection by Treponema pallidum in Pregnants of the Baixada Fluminense Region, Province of Rio de Janeiro, Brazil. Sci. J. Public Health 2016, 4(3), 224-228. doi: 10.11648/j.sjph.20160403.20

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AMA Style

Ana Carolina Torres, Antonio Neres Norberg, Fabiano Guerra Sanches, Jose Tadeu Madeira-Oliveira, Alex Nagem Machado, et al. Prevalence of Asymptomatic Infection by Treponema pallidum in Pregnants of the Baixada Fluminense Region, Province of Rio de Janeiro, Brazil. Sci J Public Health. 2016;4(3):224-228. doi: 10.11648/j.sjph.20160403.20

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@article{10.11648/j.sjph.20160403.20,
  author = {Ana Carolina Torres and Antonio Neres Norberg and Fabiano Guerra Sanches and Jose Tadeu Madeira-Oliveira and Alex Nagem Machado and Paulo Cesar Ribeiro and Nicolau Maues Serra-Freire},
  title = {Prevalence of Asymptomatic Infection by Treponema pallidum in Pregnants of the Baixada Fluminense Region, Province of Rio de Janeiro, Brazil},
  journal = {Science Journal of Public Health},
  volume = {4},
  number = {3},
  pages = {224-228},
  doi = {10.11648/j.sjph.20160403.20},
  url = {https://doi.org/10.11648/j.sjph.20160403.20},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.sjph.20160403.20},
  abstract = {Syphilis is an infectious disease with worldwide distribution caused by Treponema pallidum, and has great clinical importance when the pathogenesis is in pregnant women. The congenital disease is the result of the infection by vertical transmission of the Treponema to the fetus and can be the cause of high morbidity of the concepts during intrauterine life. It can also cause serious problems during pregnancy such as expontaneous abortus, premature babies with low weight, stillbournes, neonatal mortality, and early or late complications in children who survive to the infection. The aim of this study is to investigate the prevalence of syphilis in pregnants in obstetrics clinics in the Baixada Fluminense region and advise the seropositives for appropriate treatment and evaluate the intervention, contributing to the  eradicate to the maternal diseases and preventing the transmission of the Treponema to the concepts. During the years 2010 and 2011, venous blood samples were collected from 1183 asymptomatic adult pregnants accompanied by obstetricians to detect anti-T. pallidum. The serum obtained from the blood was frozen and stored at -20°C until the analysis by serologic reactions of Venereal Disease Research Laboratory (VDRL) and passive hemagglutination (TPHA). The results showed 28 cases were diagnosed with titers equal or superior to 1:16, suggestive of syphilitic disease, corresponding to the coefficient of prevalence of 2.37%. There were dominance of cases in pregnants in the etary group between 21 and 30 years old. There is asymptomatic infection among the examined pregnants of Baixada Fluminense region, with possible risk of vertical transmission of infection to their concepts.},
 year = {2016}
}

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TY  - JOUR
T1  - Prevalence of Asymptomatic Infection by Treponema pallidum in Pregnants of the Baixada Fluminense Region, Province of Rio de Janeiro, Brazil
AU  - Ana Carolina Torres
AU  - Antonio Neres Norberg
AU  - Fabiano Guerra Sanches
AU  - Jose Tadeu Madeira-Oliveira
AU  - Alex Nagem Machado
AU  - Paulo Cesar Ribeiro
AU  - Nicolau Maues Serra-Freire
Y1  - 2016/05/14
PY  - 2016
N1  - https://doi.org/10.11648/j.sjph.20160403.20
DO  - 10.11648/j.sjph.20160403.20
T2  - Science Journal of Public Health
JF  - Science Journal of Public Health
JO  - Science Journal of Public Health
SP  - 224
EP  - 228
PB  - Science Publishing Group
SN  - 2328-7950
UR  - https://doi.org/10.11648/j.sjph.20160403.20
AB  - Syphilis is an infectious disease with worldwide distribution caused by Treponema pallidum, and has great clinical importance when the pathogenesis is in pregnant women. The congenital disease is the result of the infection by vertical transmission of the Treponema to the fetus and can be the cause of high morbidity of the concepts during intrauterine life. It can also cause serious problems during pregnancy such as expontaneous abortus, premature babies with low weight, stillbournes, neonatal mortality, and early or late complications in children who survive to the infection. The aim of this study is to investigate the prevalence of syphilis in pregnants in obstetrics clinics in the Baixada Fluminense region and advise the seropositives for appropriate treatment and evaluate the intervention, contributing to the  eradicate to the maternal diseases and preventing the transmission of the Treponema to the concepts. During the years 2010 and 2011, venous blood samples were collected from 1183 asymptomatic adult pregnants accompanied by obstetricians to detect anti-T. pallidum. The serum obtained from the blood was frozen and stored at -20°C until the analysis by serologic reactions of Venereal Disease Research Laboratory (VDRL) and passive hemagglutination (TPHA). The results showed 28 cases were diagnosed with titers equal or superior to 1:16, suggestive of syphilitic disease, corresponding to the coefficient of prevalence of 2.37%. There were dominance of cases in pregnants in the etary group between 21 and 30 years old. There is asymptomatic infection among the examined pregnants of Baixada Fluminense region, with possible risk of vertical transmission of infection to their concepts.
VL  - 4
IS  - 3
ER  -

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Author Information

Ana Carolina Torres

Department of Pathology, Igua?u University – UNIG, Rio de Janeiro, Brazil
Antonio Neres Norberg

Department of Pathology, Souza Marques Medicine School – FTESM, Rio de Janeiro, Brazil
Fabiano Guerra Sanches

Department of Pathology, Igua?u University – UNIG, Rio de Janeiro, Brazil
Jose Tadeu Madeira-Oliveira

Department of Pathology, UNIABEU University Center, Rio de Janeiro, Brazil
Alex Nagem Machado

Department of Public Health, Medicine School of Manhua?u - FACIG, Manhua?u, Brazil
Paulo Cesar Ribeiro

Department of Pathology, Igua?u University – UNIG, Rio de Janeiro, Brazil
Nicolau Maues Serra-Freire

Department of Public Health, Oswaldo Cruz Institute – IOC/FIOCRUZ, Rio de Janeiro, Brazil

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Plain Text BibTeX RIS

APA Style

Ana Carolina Torres, Antonio Neres Norberg, Fabiano Guerra Sanches, Jose Tadeu Madeira-Oliveira, Alex Nagem Machado, et al. (2016). Prevalence of Asymptomatic Infection by Treponema pallidum in Pregnants of the Baixada Fluminense Region, Province of Rio de Janeiro, Brazil. Science Journal of Public Health, 4(3), 224-228. https://doi.org/10.11648/j.sjph.20160403.20

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ACS Style

Ana Carolina Torres; Antonio Neres Norberg; Fabiano Guerra Sanches; Jose Tadeu Madeira-Oliveira; Alex Nagem Machado, et al. Prevalence of Asymptomatic Infection by Treponema pallidum in Pregnants of the Baixada Fluminense Region, Province of Rio de Janeiro, Brazil. Sci. J. Public Health 2016, 4(3), 224-228. doi: 10.11648/j.sjph.20160403.20

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AMA Style

Ana Carolina Torres, Antonio Neres Norberg, Fabiano Guerra Sanches, Jose Tadeu Madeira-Oliveira, Alex Nagem Machado, et al. Prevalence of Asymptomatic Infection by Treponema pallidum in Pregnants of the Baixada Fluminense Region, Province of Rio de Janeiro, Brazil. Sci J Public Health. 2016;4(3):224-228. doi: 10.11648/j.sjph.20160403.20

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@article{10.11648/j.sjph.20160403.20,
  author = {Ana Carolina Torres and Antonio Neres Norberg and Fabiano Guerra Sanches and Jose Tadeu Madeira-Oliveira and Alex Nagem Machado and Paulo Cesar Ribeiro and Nicolau Maues Serra-Freire},
  title = {Prevalence of Asymptomatic Infection by Treponema pallidum in Pregnants of the Baixada Fluminense Region, Province of Rio de Janeiro, Brazil},
  journal = {Science Journal of Public Health},
  volume = {4},
  number = {3},
  pages = {224-228},
  doi = {10.11648/j.sjph.20160403.20},
  url = {https://doi.org/10.11648/j.sjph.20160403.20},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.sjph.20160403.20},
  abstract = {Syphilis is an infectious disease with worldwide distribution caused by Treponema pallidum, and has great clinical importance when the pathogenesis is in pregnant women. The congenital disease is the result of the infection by vertical transmission of the Treponema to the fetus and can be the cause of high morbidity of the concepts during intrauterine life. It can also cause serious problems during pregnancy such as expontaneous abortus, premature babies with low weight, stillbournes, neonatal mortality, and early or late complications in children who survive to the infection. The aim of this study is to investigate the prevalence of syphilis in pregnants in obstetrics clinics in the Baixada Fluminense region and advise the seropositives for appropriate treatment and evaluate the intervention, contributing to the  eradicate to the maternal diseases and preventing the transmission of the Treponema to the concepts. During the years 2010 and 2011, venous blood samples were collected from 1183 asymptomatic adult pregnants accompanied by obstetricians to detect anti-T. pallidum. The serum obtained from the blood was frozen and stored at -20°C until the analysis by serologic reactions of Venereal Disease Research Laboratory (VDRL) and passive hemagglutination (TPHA). The results showed 28 cases were diagnosed with titers equal or superior to 1:16, suggestive of syphilitic disease, corresponding to the coefficient of prevalence of 2.37%. There were dominance of cases in pregnants in the etary group between 21 and 30 years old. There is asymptomatic infection among the examined pregnants of Baixada Fluminense region, with possible risk of vertical transmission of infection to their concepts.},
 year = {2016}
}

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TY  - JOUR
T1  - Prevalence of Asymptomatic Infection by Treponema pallidum in Pregnants of the Baixada Fluminense Region, Province of Rio de Janeiro, Brazil
AU  - Ana Carolina Torres
AU  - Antonio Neres Norberg
AU  - Fabiano Guerra Sanches
AU  - Jose Tadeu Madeira-Oliveira
AU  - Alex Nagem Machado
AU  - Paulo Cesar Ribeiro
AU  - Nicolau Maues Serra-Freire
Y1  - 2016/05/14
PY  - 2016
N1  - https://doi.org/10.11648/j.sjph.20160403.20
DO  - 10.11648/j.sjph.20160403.20
T2  - Science Journal of Public Health
JF  - Science Journal of Public Health
JO  - Science Journal of Public Health
SP  - 224
EP  - 228
PB  - Science Publishing Group
SN  - 2328-7950
UR  - https://doi.org/10.11648/j.sjph.20160403.20
AB  - Syphilis is an infectious disease with worldwide distribution caused by Treponema pallidum, and has great clinical importance when the pathogenesis is in pregnant women. The congenital disease is the result of the infection by vertical transmission of the Treponema to the fetus and can be the cause of high morbidity of the concepts during intrauterine life. It can also cause serious problems during pregnancy such as expontaneous abortus, premature babies with low weight, stillbournes, neonatal mortality, and early or late complications in children who survive to the infection. The aim of this study is to investigate the prevalence of syphilis in pregnants in obstetrics clinics in the Baixada Fluminense region and advise the seropositives for appropriate treatment and evaluate the intervention, contributing to the  eradicate to the maternal diseases and preventing the transmission of the Treponema to the concepts. During the years 2010 and 2011, venous blood samples were collected from 1183 asymptomatic adult pregnants accompanied by obstetricians to detect anti-T. pallidum. The serum obtained from the blood was frozen and stored at -20°C until the analysis by serologic reactions of Venereal Disease Research Laboratory (VDRL) and passive hemagglutination (TPHA). The results showed 28 cases were diagnosed with titers equal or superior to 1:16, suggestive of syphilitic disease, corresponding to the coefficient of prevalence of 2.37%. There were dominance of cases in pregnants in the etary group between 21 and 30 years old. There is asymptomatic infection among the examined pregnants of Baixada Fluminense region, with possible risk of vertical transmission of infection to their concepts.
VL  - 4
IS  - 3
ER  -

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