Introduction: With the increase in the awareness of breast cancer among women, cases of lump in the breast has increased in outpatient department. Fine needle aspiration cytology (FNAC) is the easy, quick and cost effective technique of evaluating breast lump. Objective: The present study, evaluated and compared the modified Masood's cytology index (MCI) with various other cytology grading methods and histopathology. Result: Modified MCI has over all concordance rate of 86%, sensitivity of 86%, specificity of 50%, positive predictive value (PPV) of 93% and negative predictive value (NPV) of 30%. Multiple regression analysis revealed an r2 value of 60%, which was significant. The p-value of anisonucleosis, nucleoli and chromatin pattern were 0.001, 0.05 and 0.02 respectively, which was significant (p-value less than 0.05). Conclusion: Modified MCI will help the cytopathologist to accurately delineate both benign and malignant neoplastic breast lesions into respective categories. This in turn will help the treating surgeon to plan the treatment modality of the patients with lump in the breast. The study recommends that modified MCI method to be routinely incorporated for evaluation of all lump in the breast.
| Published in |
Science Journal of Clinical Medicine (Volume 4, Issue 4-1)
This article belongs to the Special Issue Latest Different Concepts of Gynaecology |
| DOI | 10.11648/j.sjcm.s.2015040401.17 |
| Page(s) | 26-30 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2015. Published by Science Publishing Group |
Breast, Masood Cytology Index, FNAC, Cytology
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APA Style
T. S. Rekha, N. M. Nandini. (2015). Evaluation of Breast Neoplastic Lesions by Different Cytology Grading Methods. Science Journal of Clinical Medicine, 4(4-1), 26-30. https://doi.org/10.11648/j.sjcm.s.2015040401.17
ACS Style
T. S. Rekha; N. M. Nandini. Evaluation of Breast Neoplastic Lesions by Different Cytology Grading Methods. Sci. J. Clin. Med. 2015, 4(4-1), 26-30. doi: 10.11648/j.sjcm.s.2015040401.17
AMA Style
T. S. Rekha, N. M. Nandini. Evaluation of Breast Neoplastic Lesions by Different Cytology Grading Methods. Sci J Clin Med. 2015;4(4-1):26-30. doi: 10.11648/j.sjcm.s.2015040401.17
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Download@article{10.11648/j.sjcm.s.2015040401.17,
author = {T. S. Rekha and N. M. Nandini},
title = {Evaluation of Breast Neoplastic Lesions by Different Cytology Grading Methods},
journal = {Science Journal of Clinical Medicine},
volume = {4},
number = {4-1},
pages = {26-30},
doi = {10.11648/j.sjcm.s.2015040401.17},
url = {https://doi.org/10.11648/j.sjcm.s.2015040401.17},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.sjcm.s.2015040401.17},
abstract = {Introduction: With the increase in the awareness of breast cancer among women, cases of lump in the breast has increased in outpatient department. Fine needle aspiration cytology (FNAC) is the easy, quick and cost effective technique of evaluating breast lump. Objective: The present study, evaluated and compared the modified Masood's cytology index (MCI) with various other cytology grading methods and histopathology. Result: Modified MCI has over all concordance rate of 86%, sensitivity of 86%, specificity of 50%, positive predictive value (PPV) of 93% and negative predictive value (NPV) of 30%. Multiple regression analysis revealed an r2 value of 60%, which was significant. The p-value of anisonucleosis, nucleoli and chromatin pattern were 0.001, 0.05 and 0.02 respectively, which was significant (p-value less than 0.05). Conclusion: Modified MCI will help the cytopathologist to accurately delineate both benign and malignant neoplastic breast lesions into respective categories. This in turn will help the treating surgeon to plan the treatment modality of the patients with lump in the breast. The study recommends that modified MCI method to be routinely incorporated for evaluation of all lump in the breast.},
year = {2015}
}
TY - JOUR T1 - Evaluation of Breast Neoplastic Lesions by Different Cytology Grading Methods AU - T. S. Rekha AU - N. M. Nandini Y1 - 2015/08/03 PY - 2015 N1 - https://doi.org/10.11648/j.sjcm.s.2015040401.17 DO - 10.11648/j.sjcm.s.2015040401.17 T2 - Science Journal of Clinical Medicine JF - Science Journal of Clinical Medicine JO - Science Journal of Clinical Medicine SP - 26 EP - 30 PB - Science Publishing Group SN - 2327-2732 UR - https://doi.org/10.11648/j.sjcm.s.2015040401.17 AB - Introduction: With the increase in the awareness of breast cancer among women, cases of lump in the breast has increased in outpatient department. Fine needle aspiration cytology (FNAC) is the easy, quick and cost effective technique of evaluating breast lump. Objective: The present study, evaluated and compared the modified Masood's cytology index (MCI) with various other cytology grading methods and histopathology. Result: Modified MCI has over all concordance rate of 86%, sensitivity of 86%, specificity of 50%, positive predictive value (PPV) of 93% and negative predictive value (NPV) of 30%. Multiple regression analysis revealed an r2 value of 60%, which was significant. The p-value of anisonucleosis, nucleoli and chromatin pattern were 0.001, 0.05 and 0.02 respectively, which was significant (p-value less than 0.05). Conclusion: Modified MCI will help the cytopathologist to accurately delineate both benign and malignant neoplastic breast lesions into respective categories. This in turn will help the treating surgeon to plan the treatment modality of the patients with lump in the breast. The study recommends that modified MCI method to be routinely incorporated for evaluation of all lump in the breast. VL - 4 IS - 4-1 ER -
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