PET/CT Versus CT In Post-Operative Follow Up Of Breast Cancer Patients

Hala H. Mohamed; Osama M. Ebied; Mohamed A. Hussein

doi:doi:10.11648/j.ijmi.20150302.14

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PET/CT Versus CT In Post-Operative Follow Up Of Breast Cancer Patients

Hala H. Mohamed, Osama M. Ebied, Mohamed A. Hussein

Published in International Journal of Medical Imaging (Volume 3, Issue 2)

Received: 23 February 2015 Accepted: 9 March 2015 Published: 13 March 2015

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Abstract

Objectives: The aim of this work is to compare the sensitivity and specificity of CT alone versus PET/CT in post-operative follow up of breast cancer patients. Background: Positron emission tomography (PET), using 18F-fluorodeoxyglucose (FDG) is based on the principle of increased glucose metabolism in malignant tumors and has been frequently investigated in breast cancer. Materials & Methods: Thirty female patients with breast cancer have been investigated. All patients had positive operative history. PET/CT studies were performed for post-operative follow up. The inclusion criteria in this study are histologically proved breast cancer, positive operative history and normal blood urea and creatinine levels. Exclusion criteria is pregnancy and renal impairment. Patients were divided into three groups, first group FDG PET/CT was requested for non-conclusive CT findings, second group patients referred for FDG PET/CT for elevated tumor markers, while in third group FDG PET/CT was requested for follow up after chemotherapy and/or radiotherapy. Results: A comparison of the sensitivity and specificity for CT alone versus PET/CT in each group, in the first group CT alone had sensitivity and specificity of 90% and 12.5% respectively, while PET/CT had sensitivity and specificity 100%. In the second group CT alone had sensitivity and specificity of 57% and 100% respectively, while PET/CT had sensitivity and specificity of 100%. In group three, CT alone had sensitivity and specificity of 83.3% and 84.25%, respectively and PET/CT had sensitivity of 83.3% and specificity of 100%.Conclusions: PET/CT is more sensitive and specific than CT alone for post-operative follow up of breast cancer patients.

Published in	International Journal of Medical Imaging (Volume 3, Issue 2)
DOI	10.11648/j.ijmi.20150302.14
Page(s)	28-33
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2015. Published by Science Publishing Group

Keywords

Positron Emission Tomography, Computed Tomography, Breast

References

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APA Style

Hala H. Mohamed, Osama M. Ebied, Mohamed A. Hussein. (2015). PET/CT Versus CT In Post-Operative Follow Up Of Breast Cancer Patients. International Journal of Medical Imaging, 3(2), 28-33. https://doi.org/10.11648/j.ijmi.20150302.14

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ACS Style

Hala H. Mohamed; Osama M. Ebied; Mohamed A. Hussein. PET/CT Versus CT In Post-Operative Follow Up Of Breast Cancer Patients. Int. J. Med. Imaging 2015, 3(2), 28-33. doi: 10.11648/j.ijmi.20150302.14

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AMA Style

Hala H. Mohamed, Osama M. Ebied, Mohamed A. Hussein. PET/CT Versus CT In Post-Operative Follow Up Of Breast Cancer Patients. Int J Med Imaging. 2015;3(2):28-33. doi: 10.11648/j.ijmi.20150302.14

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@article{10.11648/j.ijmi.20150302.14,
  author = {Hala H. Mohamed and Osama M. Ebied and Mohamed A. Hussein},
  title = {PET/CT Versus CT In Post-Operative Follow Up Of Breast Cancer Patients},
  journal = {International Journal of Medical Imaging},
  volume = {3},
  number = {2},
  pages = {28-33},
  doi = {10.11648/j.ijmi.20150302.14},
  url = {https://doi.org/10.11648/j.ijmi.20150302.14},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijmi.20150302.14},
  abstract = {Objectives: The aim of this work is to compare the sensitivity and specificity of CT alone versus PET/CT in post-operative follow up of breast cancer patients. Background: Positron emission tomography (PET), using 18F-fluorodeoxyglucose (FDG) is based on the principle of increased glucose metabolism in malignant tumors and has been frequently investigated in breast cancer. Materials & Methods: Thirty female patients with breast cancer have been investigated. All patients had positive operative history. PET/CT studies were performed for post-operative follow up. The inclusion criteria in this study are histologically proved breast cancer, positive operative history and normal blood urea and creatinine levels. Exclusion criteria is pregnancy and renal impairment. Patients were divided into three groups, first group FDG PET/CT was requested for non-conclusive CT findings, second group patients referred for FDG PET/CT for elevated tumor markers, while in third group FDG PET/CT was requested for follow up after chemotherapy and/or radiotherapy. Results: A comparison of the sensitivity and specificity for CT alone versus PET/CT in each group, in the first group CT alone had sensitivity and specificity of 90% and 12.5% respectively, while PET/CT had sensitivity and specificity 100%. In the second group CT alone had sensitivity and specificity of 57% and 100% respectively, while PET/CT had sensitivity and specificity of 100%. In group three, CT alone had sensitivity and specificity of 83.3% and 84.25%, respectively and PET/CT had sensitivity of 83.3% and specificity of 100%.Conclusions: PET/CT is more sensitive and specific than CT alone for post-operative follow up of breast cancer patients.},
 year = {2015}
}

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TY - JOUR
T1 - PET/CT Versus CT In Post-Operative Follow Up Of Breast Cancer Patients
AU - Hala H. Mohamed
AU - Osama M. Ebied
AU - Mohamed A. Hussein
Y1 - 2015/03/13
PY - 2015
N1 - https://doi.org/10.11648/j.ijmi.20150302.14
DO - 10.11648/j.ijmi.20150302.14
T2 - International Journal of Medical Imaging
JF - International Journal of Medical Imaging
JO - International Journal of Medical Imaging
SP - 28
EP - 33
PB - Science Publishing Group
SN - 2330-832X
UR - https://doi.org/10.11648/j.ijmi.20150302.14
AB - Objectives: The aim of this work is to compare the sensitivity and specificity of CT alone versus PET/CT in post-operative follow up of breast cancer patients. Background: Positron emission tomography (PET), using 18F-fluorodeoxyglucose (FDG) is based on the principle of increased glucose metabolism in malignant tumors and has been frequently investigated in breast cancer. Materials & Methods: Thirty female patients with breast cancer have been investigated. All patients had positive operative history. PET/CT studies were performed for post-operative follow up. The inclusion criteria in this study are histologically proved breast cancer, positive operative history and normal blood urea and creatinine levels. Exclusion criteria is pregnancy and renal impairment. Patients were divided into three groups, first group FDG PET/CT was requested for non-conclusive CT findings, second group patients referred for FDG PET/CT for elevated tumor markers, while in third group FDG PET/CT was requested for follow up after chemotherapy and/or radiotherapy. Results: A comparison of the sensitivity and specificity for CT alone versus PET/CT in each group, in the first group CT alone had sensitivity and specificity of 90% and 12.5% respectively, while PET/CT had sensitivity and specificity 100%. In the second group CT alone had sensitivity and specificity of 57% and 100% respectively, while PET/CT had sensitivity and specificity of 100%. In group three, CT alone had sensitivity and specificity of 83.3% and 84.25%, respectively and PET/CT had sensitivity of 83.3% and specificity of 100%.Conclusions: PET/CT is more sensitive and specific than CT alone for post-operative follow up of breast cancer patients.
VL - 3
IS - 2
ER -

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Author Information

Hala H. Mohamed

Department of Radiodiagnosis, Faculty of Medicine, Menoufia University, Menoufia, Egypt
Osama M. Ebied

Department of Radiodiagnosis, Faculty of Medicine, Menoufia University, Menoufia, Egypt
Mohamed A. Hussein

Department of Radiodiagnosis, Shareq El-Madina Hospital, Alexandria, Egypt

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APA Style

Hala H. Mohamed, Osama M. Ebied, Mohamed A. Hussein. (2015). PET/CT Versus CT In Post-Operative Follow Up Of Breast Cancer Patients. International Journal of Medical Imaging, 3(2), 28-33. https://doi.org/10.11648/j.ijmi.20150302.14

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ACS Style

Hala H. Mohamed; Osama M. Ebied; Mohamed A. Hussein. PET/CT Versus CT In Post-Operative Follow Up Of Breast Cancer Patients. Int. J. Med. Imaging 2015, 3(2), 28-33. doi: 10.11648/j.ijmi.20150302.14

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AMA Style

Hala H. Mohamed, Osama M. Ebied, Mohamed A. Hussein. PET/CT Versus CT In Post-Operative Follow Up Of Breast Cancer Patients. Int J Med Imaging. 2015;3(2):28-33. doi: 10.11648/j.ijmi.20150302.14

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@article{10.11648/j.ijmi.20150302.14,
  author = {Hala H. Mohamed and Osama M. Ebied and Mohamed A. Hussein},
  title = {PET/CT Versus CT In Post-Operative Follow Up Of Breast Cancer Patients},
  journal = {International Journal of Medical Imaging},
  volume = {3},
  number = {2},
  pages = {28-33},
  doi = {10.11648/j.ijmi.20150302.14},
  url = {https://doi.org/10.11648/j.ijmi.20150302.14},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijmi.20150302.14},
  abstract = {Objectives: The aim of this work is to compare the sensitivity and specificity of CT alone versus PET/CT in post-operative follow up of breast cancer patients. Background: Positron emission tomography (PET), using 18F-fluorodeoxyglucose (FDG) is based on the principle of increased glucose metabolism in malignant tumors and has been frequently investigated in breast cancer. Materials & Methods: Thirty female patients with breast cancer have been investigated. All patients had positive operative history. PET/CT studies were performed for post-operative follow up. The inclusion criteria in this study are histologically proved breast cancer, positive operative history and normal blood urea and creatinine levels. Exclusion criteria is pregnancy and renal impairment. Patients were divided into three groups, first group FDG PET/CT was requested for non-conclusive CT findings, second group patients referred for FDG PET/CT for elevated tumor markers, while in third group FDG PET/CT was requested for follow up after chemotherapy and/or radiotherapy. Results: A comparison of the sensitivity and specificity for CT alone versus PET/CT in each group, in the first group CT alone had sensitivity and specificity of 90% and 12.5% respectively, while PET/CT had sensitivity and specificity 100%. In the second group CT alone had sensitivity and specificity of 57% and 100% respectively, while PET/CT had sensitivity and specificity of 100%. In group three, CT alone had sensitivity and specificity of 83.3% and 84.25%, respectively and PET/CT had sensitivity of 83.3% and specificity of 100%.Conclusions: PET/CT is more sensitive and specific than CT alone for post-operative follow up of breast cancer patients.},
 year = {2015}
}

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