Micro RNA are the noncoding class of RNA which plays major role post transcriptional regulation of genes and 19-22 nt in length and endogenous in nature .In this study miRNA Gmelina arborea are predicted along with possible target genes , A total of 44 ESTs are taken from dbEST database and proceed and trimmed through EGassembler. This contig sequence was now used to find out the putative miRNA by performing a local alignment with miRNA of Arabidopsis thaliana retrieved from miRBase. The targets were scanned by hybridizing screened ESTs with the UTRs of human using DIANA tar software. Finally 6 putative miRNAs were found to hybridize with the various targets of signal transduction and apoptosis that play significant role in preventing disease like cancer, blood borne disease, and other urinary infections and various study indicated that is possesses antioxidants, diuretic, anthelmintic activity, cardio protective, anti diabetic, immunomodulatory, antipyretic and analgesic, antimicrobial in the treatment of jaundice, piles bases on their targets
| Published in | American Journal of Bioscience and Bioengineering (Volume 1, Issue 5) |
| DOI | 10.11648/j.bio.20130105.12 |
| Page(s) | 62-74 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2013. Published by Science Publishing Group |
Gmelina Arborea, miRNA, Dbest, DIANA, Local Alignment
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APA Style
Alka Dubey, Swinderjeet Singh Kalra, Nandita Trivedi. (2013). Computational Prediction of miRNA in Gmelina Arborea and their Role in Human Metabolomics. American Journal of Bioscience and Bioengineering, 1(5), 62-74. https://doi.org/10.11648/j.bio.20130105.12
ACS Style
Alka Dubey; Swinderjeet Singh Kalra; Nandita Trivedi. Computational Prediction of miRNA in Gmelina Arborea and their Role in Human Metabolomics. Am. J. BioSci. Bioeng. 2013, 1(5), 62-74. doi: 10.11648/j.bio.20130105.12
AMA Style
Alka Dubey, Swinderjeet Singh Kalra, Nandita Trivedi. Computational Prediction of miRNA in Gmelina Arborea and their Role in Human Metabolomics. Am J BioSci Bioeng. 2013;1(5):62-74. doi: 10.11648/j.bio.20130105.12
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Download@article{10.11648/j.bio.20130105.12,
author = {Alka Dubey and Swinderjeet Singh Kalra and Nandita Trivedi},
title = {Computational Prediction of miRNA in Gmelina Arborea and their Role in Human Metabolomics},
journal = {American Journal of Bioscience and Bioengineering},
volume = {1},
number = {5},
pages = {62-74},
doi = {10.11648/j.bio.20130105.12},
url = {https://doi.org/10.11648/j.bio.20130105.12},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.bio.20130105.12},
abstract = {Micro RNA are the noncoding class of RNA which plays major role post transcriptional regulation of genes and 19-22 nt in length and endogenous in nature .In this study miRNA Gmelina arborea are predicted along with possible target genes , A total of 44 ESTs are taken from dbEST database and proceed and trimmed through EGassembler. This contig sequence was now used to find out the putative miRNA by performing a local alignment with miRNA of Arabidopsis thaliana retrieved from miRBase. The targets were scanned by hybridizing screened ESTs with the UTRs of human using DIANA tar software. Finally 6 putative miRNAs were found to hybridize with the various targets of signal transduction and apoptosis that play significant role in preventing disease like cancer, blood borne disease, and other urinary infections and various study indicated that is possesses antioxidants, diuretic, anthelmintic activity, cardio protective, anti diabetic, immunomodulatory, antipyretic and analgesic, antimicrobial in the treatment of jaundice, piles bases on their targets},
year = {2013}
}
TY - JOUR T1 - Computational Prediction of miRNA in Gmelina Arborea and their Role in Human Metabolomics AU - Alka Dubey AU - Swinderjeet Singh Kalra AU - Nandita Trivedi Y1 - 2013/09/30 PY - 2013 N1 - https://doi.org/10.11648/j.bio.20130105.12 DO - 10.11648/j.bio.20130105.12 T2 - American Journal of Bioscience and Bioengineering JF - American Journal of Bioscience and Bioengineering JO - American Journal of Bioscience and Bioengineering SP - 62 EP - 74 PB - Science Publishing Group SN - 2328-5893 UR - https://doi.org/10.11648/j.bio.20130105.12 AB - Micro RNA are the noncoding class of RNA which plays major role post transcriptional regulation of genes and 19-22 nt in length and endogenous in nature .In this study miRNA Gmelina arborea are predicted along with possible target genes , A total of 44 ESTs are taken from dbEST database and proceed and trimmed through EGassembler. This contig sequence was now used to find out the putative miRNA by performing a local alignment with miRNA of Arabidopsis thaliana retrieved from miRBase. The targets were scanned by hybridizing screened ESTs with the UTRs of human using DIANA tar software. Finally 6 putative miRNAs were found to hybridize with the various targets of signal transduction and apoptosis that play significant role in preventing disease like cancer, blood borne disease, and other urinary infections and various study indicated that is possesses antioxidants, diuretic, anthelmintic activity, cardio protective, anti diabetic, immunomodulatory, antipyretic and analgesic, antimicrobial in the treatment of jaundice, piles bases on their targets VL - 1 IS - 5 ER -
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