The Choice of Informative Parameters of the Cardiovascular System for Assessment of Physiological Effects of Hypogravity

Anton Cherepov; Daria Pozdeeva; Elena Arkhipova

doi:doi:10.11648/j.ajls.s.2015030102.18

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The Choice of Informative Parameters of the Cardiovascular System for Assessment of Physiological Effects of Hypogravity

Anton Cherepov, Daria Pozdeeva, Elena Arkhipova

Published in American Journal of Life Sciences (Volume 3, Issue 1-2)

Received: 19 December 2014 Accepted: 23 December 2014 Published: 31 December 2014

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Abstract

Changes in cardiovascular system (CVS) under conditions of hypogravity simulated using 7- and 21-day ortho- and antiorthostatic hypokinesia at different angles were studied. The aim of the experiment was selection of informative CVS parameters most sensitive to these conditions. Simultaneous recording of 26 CVS parameters on a spiroartheriocardiorythmograph showed that the most sensitive parameters were blood pressure (BP) variability indexes in functional tests: differences in groups with varying degrees of orthostatic hypokinesia (+ 9.6˚ and + 15˚) were observed starting from the first week of the experiment. By day 21, pronounced changes in the total spectral power of diastolic BP variability were noted in the group exposed to constant antiorthostasis. This parameter significantly surpassed the corresponding value in the groups with milder conditions. Significant increase in the LF component of diastolic BP in groups exposed to severe antiorthostasis and orthostasis was detected. Presumably, autonomic mechanisms affecting the systolic and diastolic BP under conditions of hypogravity simulation are different, at least partially.

Published in	American Journal of Life Sciences (Volume 3, Issue 1-2) This article belongs to the Special Issue Space Flight Factors: From Cell to Body
DOI	10.11648/j.ajls.s.2015030102.18
Page(s)	48-57
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2014. Published by Science Publishing Group

Keywords

Systolic and Diastolic Blood Pressure, Simulated Hypogravity, Bed Rest, Heart rate Variability, Blood Pressure Variability

References

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APA Style

Anton Cherepov, Daria Pozdeeva, Elena Arkhipova. (2014). The Choice of Informative Parameters of the Cardiovascular System for Assessment of Physiological Effects of Hypogravity. American Journal of Life Sciences, 3(1-2), 48-57. https://doi.org/10.11648/j.ajls.s.2015030102.18

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ACS Style

Anton Cherepov; Daria Pozdeeva; Elena Arkhipova. The Choice of Informative Parameters of the Cardiovascular System for Assessment of Physiological Effects of Hypogravity. Am. J. Life Sci. 2014, 3(1-2), 48-57. doi: 10.11648/j.ajls.s.2015030102.18

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AMA Style

Anton Cherepov, Daria Pozdeeva, Elena Arkhipova. The Choice of Informative Parameters of the Cardiovascular System for Assessment of Physiological Effects of Hypogravity. Am J Life Sci. 2014;3(1-2):48-57. doi: 10.11648/j.ajls.s.2015030102.18

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@article{10.11648/j.ajls.s.2015030102.18,
  author = {Anton Cherepov and Daria Pozdeeva and Elena Arkhipova},
  title = {The Choice of Informative Parameters of the Cardiovascular System for Assessment of Physiological Effects of Hypogravity},
  journal = {American Journal of Life Sciences},
  volume = {3},
  number = {1-2},
  pages = {48-57},
  doi = {10.11648/j.ajls.s.2015030102.18},
  url = {https://doi.org/10.11648/j.ajls.s.2015030102.18},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajls.s.2015030102.18},
  abstract = {Changes in cardiovascular system (CVS) under conditions of hypogravity simulated using 7- and 21-day ortho- and antiorthostatic hypokinesia at different angles were studied. The aim of the experiment was selection of informative CVS parameters most sensitive to these conditions. Simultaneous recording of 26 CVS parameters on a spiroartheriocardiorythmograph showed that the most sensitive parameters were blood pressure (BP) variability indexes in functional tests: differences in groups with varying degrees of orthostatic hypokinesia (+ 9.6˚ and + 15˚) were observed starting from the first week of the experiment. By day 21, pronounced changes in the total spectral power of diastolic BP variability were noted in the group exposed to constant antiorthostasis. This parameter significantly surpassed the corresponding value in the groups with milder conditions. Significant increase in the LF component of diastolic BP in groups exposed to severe antiorthostasis and orthostasis was detected. Presumably, autonomic mechanisms affecting the systolic and diastolic BP under conditions of hypogravity simulation are different, at least partially.},
 year = {2014}
}

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TY  - JOUR
T1  - The Choice of Informative Parameters of the Cardiovascular System for Assessment of Physiological Effects of Hypogravity
AU  - Anton Cherepov
AU  - Daria Pozdeeva
AU  - Elena Arkhipova
Y1  - 2014/12/31
PY  - 2014
N1  - https://doi.org/10.11648/j.ajls.s.2015030102.18
DO  - 10.11648/j.ajls.s.2015030102.18
T2  - American Journal of Life Sciences
JF  - American Journal of Life Sciences
JO  - American Journal of Life Sciences
SP  - 48
EP  - 57
PB  - Science Publishing Group
SN  - 2328-5737
UR  - https://doi.org/10.11648/j.ajls.s.2015030102.18
AB  - Changes in cardiovascular system (CVS) under conditions of hypogravity simulated using 7- and 21-day ortho- and antiorthostatic hypokinesia at different angles were studied. The aim of the experiment was selection of informative CVS parameters most sensitive to these conditions. Simultaneous recording of 26 CVS parameters on a spiroartheriocardiorythmograph showed that the most sensitive parameters were blood pressure (BP) variability indexes in functional tests: differences in groups with varying degrees of orthostatic hypokinesia (+ 9.6˚ and + 15˚) were observed starting from the first week of the experiment. By day 21, pronounced changes in the total spectral power of diastolic BP variability were noted in the group exposed to constant antiorthostasis. This parameter significantly surpassed the corresponding value in the groups with milder conditions. Significant increase in the LF component of diastolic BP in groups exposed to severe antiorthostasis and orthostasis was detected. Presumably, autonomic mechanisms affecting the systolic and diastolic BP under conditions of hypogravity simulation are different, at least partially.
VL  - 3
IS  - 1-2
ER  -

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Author Information

Anton Cherepov

Lab of Neurobiology of Memory, P. K. Anokhin Institute of Normal Physiology, Moscow, Russia
Daria Pozdeeva

Lab of Physicochemical and Ecological Pathophysiology, Institute of General Pathology and Pathophysiology, Moscow, Russia
Elena Arkhipova

Lab of Physicochemical and Ecological Pathophysiology, Institute of General Pathology and Pathophysiology, Moscow, Russia

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APA Style

Anton Cherepov, Daria Pozdeeva, Elena Arkhipova. (2014). The Choice of Informative Parameters of the Cardiovascular System for Assessment of Physiological Effects of Hypogravity. American Journal of Life Sciences, 3(1-2), 48-57. https://doi.org/10.11648/j.ajls.s.2015030102.18

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ACS Style

Anton Cherepov; Daria Pozdeeva; Elena Arkhipova. The Choice of Informative Parameters of the Cardiovascular System for Assessment of Physiological Effects of Hypogravity. Am. J. Life Sci. 2014, 3(1-2), 48-57. doi: 10.11648/j.ajls.s.2015030102.18

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AMA Style

Anton Cherepov, Daria Pozdeeva, Elena Arkhipova. The Choice of Informative Parameters of the Cardiovascular System for Assessment of Physiological Effects of Hypogravity. Am J Life Sci. 2014;3(1-2):48-57. doi: 10.11648/j.ajls.s.2015030102.18

Copy | Download

@article{10.11648/j.ajls.s.2015030102.18,
  author = {Anton Cherepov and Daria Pozdeeva and Elena Arkhipova},
  title = {The Choice of Informative Parameters of the Cardiovascular System for Assessment of Physiological Effects of Hypogravity},
  journal = {American Journal of Life Sciences},
  volume = {3},
  number = {1-2},
  pages = {48-57},
  doi = {10.11648/j.ajls.s.2015030102.18},
  url = {https://doi.org/10.11648/j.ajls.s.2015030102.18},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajls.s.2015030102.18},
  abstract = {Changes in cardiovascular system (CVS) under conditions of hypogravity simulated using 7- and 21-day ortho- and antiorthostatic hypokinesia at different angles were studied. The aim of the experiment was selection of informative CVS parameters most sensitive to these conditions. Simultaneous recording of 26 CVS parameters on a spiroartheriocardiorythmograph showed that the most sensitive parameters were blood pressure (BP) variability indexes in functional tests: differences in groups with varying degrees of orthostatic hypokinesia (+ 9.6˚ and + 15˚) were observed starting from the first week of the experiment. By day 21, pronounced changes in the total spectral power of diastolic BP variability were noted in the group exposed to constant antiorthostasis. This parameter significantly surpassed the corresponding value in the groups with milder conditions. Significant increase in the LF component of diastolic BP in groups exposed to severe antiorthostasis and orthostasis was detected. Presumably, autonomic mechanisms affecting the systolic and diastolic BP under conditions of hypogravity simulation are different, at least partially.},
 year = {2014}
}

Copy | Download

TY  - JOUR
T1  - The Choice of Informative Parameters of the Cardiovascular System for Assessment of Physiological Effects of Hypogravity
AU  - Anton Cherepov
AU  - Daria Pozdeeva
AU  - Elena Arkhipova
Y1  - 2014/12/31
PY  - 2014
N1  - https://doi.org/10.11648/j.ajls.s.2015030102.18
DO  - 10.11648/j.ajls.s.2015030102.18
T2  - American Journal of Life Sciences
JF  - American Journal of Life Sciences
JO  - American Journal of Life Sciences
SP  - 48
EP  - 57
PB  - Science Publishing Group
SN  - 2328-5737
UR  - https://doi.org/10.11648/j.ajls.s.2015030102.18
AB  - Changes in cardiovascular system (CVS) under conditions of hypogravity simulated using 7- and 21-day ortho- and antiorthostatic hypokinesia at different angles were studied. The aim of the experiment was selection of informative CVS parameters most sensitive to these conditions. Simultaneous recording of 26 CVS parameters on a spiroartheriocardiorythmograph showed that the most sensitive parameters were blood pressure (BP) variability indexes in functional tests: differences in groups with varying degrees of orthostatic hypokinesia (+ 9.6˚ and + 15˚) were observed starting from the first week of the experiment. By day 21, pronounced changes in the total spectral power of diastolic BP variability were noted in the group exposed to constant antiorthostasis. This parameter significantly surpassed the corresponding value in the groups with milder conditions. Significant increase in the LF component of diastolic BP in groups exposed to severe antiorthostasis and orthostasis was detected. Presumably, autonomic mechanisms affecting the systolic and diastolic BP under conditions of hypogravity simulation are different, at least partially.
VL  - 3
IS  - 1-2
ER  -

Copy | Download