Abnormal serum uric acid (UA) level is a highly prevalent condition worldwide and is increasing in the general population. This alarming epidemiological trend has enormous public health implications due to the central role of abnormal serum UA levels in the initiation, progression, and long-term effects of many metabolic and systemic diseases. Metabolic disorders are major causes of global morbidity and mortality. Altered serum UA level, both above and below the reference ranges for individual traits and contexts, is potentially harmful and described by many researchers as a double-edged sword. Concrete prevention plans in susceptible individuals and treatments to restore normal levels in individuals already affected are advocated. Lifestyle adjustment, including regular moderate physical activity, weight management, healthy eating, and regular serum UA screening are recommended for individuals susceptible to derangement in serum UA levels due to age, sex, genetics, and other acquired conditions. Public health efforts to create awareness about the menace of abnormal serum UA levels, particularly in susceptible individuals, should be encouraged.
| Published in | American Journal of Internal Medicine (Volume 2, Issue 6) |
| DOI | 10.11648/j.ajim.20140206.15 |
| Page(s) | 113-130 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2014. Published by Science Publishing Group |
Deranged Serum Uric Acid, Adverse Health Effect, Human
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APA Style
Christopher Ekpenyong, Ernest Akpan. (2014). Abnormal Serum Uric Acid Levels in Health and Disease: A Double-Edged Sword. American Journal of Internal Medicine, 2(6), 113-130. https://doi.org/10.11648/j.ajim.20140206.15
ACS Style
Christopher Ekpenyong; Ernest Akpan. Abnormal Serum Uric Acid Levels in Health and Disease: A Double-Edged Sword. Am. J. Intern. Med. 2014, 2(6), 113-130. doi: 10.11648/j.ajim.20140206.15
AMA Style
Christopher Ekpenyong, Ernest Akpan. Abnormal Serum Uric Acid Levels in Health and Disease: A Double-Edged Sword. Am J Intern Med. 2014;2(6):113-130. doi: 10.11648/j.ajim.20140206.15
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Download@article{10.11648/j.ajim.20140206.15,
author = {Christopher Ekpenyong and Ernest Akpan},
title = {Abnormal Serum Uric Acid Levels in Health and Disease: A Double-Edged Sword},
journal = {American Journal of Internal Medicine},
volume = {2},
number = {6},
pages = {113-130},
doi = {10.11648/j.ajim.20140206.15},
url = {https://doi.org/10.11648/j.ajim.20140206.15},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajim.20140206.15},
abstract = {Abnormal serum uric acid (UA) level is a highly prevalent condition worldwide and is increasing in the general population. This alarming epidemiological trend has enormous public health implications due to the central role of abnormal serum UA levels in the initiation, progression, and long-term effects of many metabolic and systemic diseases. Metabolic disorders are major causes of global morbidity and mortality. Altered serum UA level, both above and below the reference ranges for individual traits and contexts, is potentially harmful and described by many researchers as a double-edged sword. Concrete prevention plans in susceptible individuals and treatments to restore normal levels in individuals already affected are advocated. Lifestyle adjustment, including regular moderate physical activity, weight management, healthy eating, and regular serum UA screening are recommended for individuals susceptible to derangement in serum UA levels due to age, sex, genetics, and other acquired conditions. Public health efforts to create awareness about the menace of abnormal serum UA levels, particularly in susceptible individuals, should be encouraged.},
year = {2014}
}
TY - JOUR T1 - Abnormal Serum Uric Acid Levels in Health and Disease: A Double-Edged Sword AU - Christopher Ekpenyong AU - Ernest Akpan Y1 - 2014/12/02 PY - 2014 N1 - https://doi.org/10.11648/j.ajim.20140206.15 DO - 10.11648/j.ajim.20140206.15 T2 - American Journal of Internal Medicine JF - American Journal of Internal Medicine JO - American Journal of Internal Medicine SP - 113 EP - 130 PB - Science Publishing Group SN - 2330-4324 UR - https://doi.org/10.11648/j.ajim.20140206.15 AB - Abnormal serum uric acid (UA) level is a highly prevalent condition worldwide and is increasing in the general population. This alarming epidemiological trend has enormous public health implications due to the central role of abnormal serum UA levels in the initiation, progression, and long-term effects of many metabolic and systemic diseases. Metabolic disorders are major causes of global morbidity and mortality. Altered serum UA level, both above and below the reference ranges for individual traits and contexts, is potentially harmful and described by many researchers as a double-edged sword. Concrete prevention plans in susceptible individuals and treatments to restore normal levels in individuals already affected are advocated. Lifestyle adjustment, including regular moderate physical activity, weight management, healthy eating, and regular serum UA screening are recommended for individuals susceptible to derangement in serum UA levels due to age, sex, genetics, and other acquired conditions. Public health efforts to create awareness about the menace of abnormal serum UA levels, particularly in susceptible individuals, should be encouraged. VL - 2 IS - 6 ER -
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