Interconnection of Antitoxic and Antioxidant Systems of the Organism under the Action of Natural Low Molecular Complex – Fungidol

Natalia Igorevna Kurguzova; Anatoliy Ivanovich Bozhkov; Yuriy Viktorovich Nikitchenko; Mohammad Ali Yousef Al Begai; Anatoliy Vladimirovich Goltvyansky; Mohammad Morshed Ayed Alsardia; Andrew Anatolievich Bozhkov

doi:doi:10.11648/j.ajbls.s.2014020601.15

Interconnection of Antitoxic and Antioxidant Systems of the Organism under the Action of Natural Low Molecular Complex – Fungidol

Natalia Igorevna Kurguzova, Anatoliy Ivanovich Bozhkov, Yuriy Viktorovich Nikitchenko, Mohammad Ali Yousef Al Begai, Anatoliy Vladimirovich Goltvyansky, Mohammad Morshed Ayed Alsardia, Andrew Anatolievich Bozhkov

Published in American Journal of Biomedical and Life Sciences (Volume 2, Issue 6-1)

Received: 23 December 2014 Accepted: 10 January 2015 Published: 23 January 2015

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Abstract

The influence of the natural complex of low molecular weight compounds (fungidol) on antitoxic and antioxidant systems in animals was investigated. It was demonstrated that the introduction to the experimental animals of fungidol in doses a 0.05 ml per 100 g of body weight increases antioxidant enzymes activity in serum and liver, decreases the content of lipids hydroperoxides and other products of free radical reactions. The components of fungidol antioxidant activity correlated with the stability of membranes of erythrocytes in these animals. In the experimental model the toxic effect of copper sulfate was investigated. The increase in the activity of prooxidant system induced by fungidol correlated with its antitoxic effect.

Published in	American Journal of Biomedical and Life Sciences (Volume 2, Issue 6-1) This article belongs to the Special Issue Mechanisms of Protection Against Oxidative Stress
DOI	10.11648/j.ajbls.s.2014020601.15
Page(s)	25-32
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2015. Published by Science Publishing Group

Keywords

Antioxidant System, Antitoxic Activity, Prooxidant Activity, Fungidol

References

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APA Style

Natalia Igorevna Kurguzova, Anatoliy Ivanovich Bozhkov, Yuriy Viktorovich Nikitchenko, Mohammad Ali Yousef Al Begai, Anatoliy Vladimirovich Goltvyansky, et al. (2015). Interconnection of Antitoxic and Antioxidant Systems of the Organism under the Action of Natural Low Molecular Complex – Fungidol. American Journal of Biomedical and Life Sciences, 2(6-1), 25-32. https://doi.org/10.11648/j.ajbls.s.2014020601.15

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ACS Style

Natalia Igorevna Kurguzova; Anatoliy Ivanovich Bozhkov; Yuriy Viktorovich Nikitchenko; Mohammad Ali Yousef Al Begai; Anatoliy Vladimirovich Goltvyansky, et al. Interconnection of Antitoxic and Antioxidant Systems of the Organism under the Action of Natural Low Molecular Complex – Fungidol. Am. J. Biomed. Life Sci. 2015, 2(6-1), 25-32. doi: 10.11648/j.ajbls.s.2014020601.15

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AMA Style

Natalia Igorevna Kurguzova, Anatoliy Ivanovich Bozhkov, Yuriy Viktorovich Nikitchenko, Mohammad Ali Yousef Al Begai, Anatoliy Vladimirovich Goltvyansky, et al. Interconnection of Antitoxic and Antioxidant Systems of the Organism under the Action of Natural Low Molecular Complex – Fungidol. Am J Biomed Life Sci. 2015;2(6-1):25-32. doi: 10.11648/j.ajbls.s.2014020601.15

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@article{10.11648/j.ajbls.s.2014020601.15,
  author = {Natalia Igorevna Kurguzova and Anatoliy Ivanovich Bozhkov and Yuriy Viktorovich Nikitchenko and Mohammad Ali Yousef Al Begai and Anatoliy Vladimirovich Goltvyansky and Mohammad Morshed Ayed Alsardia and Andrew Anatolievich Bozhkov},
  title = {Interconnection of Antitoxic and Antioxidant Systems of the Organism under the Action of Natural Low Molecular Complex – Fungidol},
  journal = {American Journal of Biomedical and Life Sciences},
  volume = {2},
  number = {6-1},
  pages = {25-32},
  doi = {10.11648/j.ajbls.s.2014020601.15},
  url = {https://doi.org/10.11648/j.ajbls.s.2014020601.15},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajbls.s.2014020601.15},
  abstract = {The influence of the natural complex of low molecular weight compounds (fungidol) on antitoxic and antioxidant systems in animals was investigated. It was demonstrated that the introduction to the experimental animals of fungidol in doses a 0.05 ml per 100 g of body weight increases antioxidant enzymes activity in serum and liver, decreases the content of lipids hydroperoxides and other products of free radical reactions. The components of fungidol antioxidant activity correlated with the stability of membranes of erythrocytes in these animals. In the experimental model the toxic effect of copper sulfate was investigated. The increase in the activity of prooxidant system induced by fungidol correlated with its antitoxic effect.},
 year = {2015}
}

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TY  - JOUR
T1  - Interconnection of Antitoxic and Antioxidant Systems of the Organism under the Action of Natural Low Molecular Complex – Fungidol
AU  - Natalia Igorevna Kurguzova
AU  - Anatoliy Ivanovich Bozhkov
AU  - Yuriy Viktorovich Nikitchenko
AU  - Mohammad Ali Yousef Al Begai
AU  - Anatoliy Vladimirovich Goltvyansky
AU  - Mohammad Morshed Ayed Alsardia
AU  - Andrew Anatolievich Bozhkov
Y1  - 2015/01/23
PY  - 2015
N1  - https://doi.org/10.11648/j.ajbls.s.2014020601.15
DO  - 10.11648/j.ajbls.s.2014020601.15
T2  - American Journal of Biomedical and Life Sciences
JF  - American Journal of Biomedical and Life Sciences
JO  - American Journal of Biomedical and Life Sciences
SP  - 25
EP  - 32
PB  - Science Publishing Group
SN  - 2330-880X
UR  - https://doi.org/10.11648/j.ajbls.s.2014020601.15
AB  - The influence of the natural complex of low molecular weight compounds (fungidol) on antitoxic and antioxidant systems in animals was investigated. It was demonstrated that the introduction to the experimental animals of fungidol in doses a 0.05 ml per 100 g of body weight increases antioxidant enzymes activity in serum and liver, decreases the content of lipids hydroperoxides and other products of free radical reactions. The components of fungidol antioxidant activity correlated with the stability of membranes of erythrocytes in these animals. In the experimental model the toxic effect of copper sulfate was investigated. The increase in the activity of prooxidant system induced by fungidol correlated with its antitoxic effect.
VL  - 2
IS  - 6-1
ER  -

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Author Information

Natalia Igorevna Kurguzova

Biology Research Institute of V. N. Karazin Kharkov National University, Kharkov, Ukraine
Anatoliy Ivanovich Bozhkov

Biology Research Institute of V. N. Karazin Kharkov National University, Kharkov, Ukraine
Yuriy Viktorovich Nikitchenko

Biology Research Institute of V. N. Karazin Kharkov National University, Kharkov, Ukraine
Mohammad Ali Yousef Al Begai

Biology Research Institute of V. N. Karazin Kharkov National University, Kharkov, Ukraine
Anatoliy Vladimirovich Goltvyansky

Biology Research Institute of V. N. Karazin Kharkov National University, Kharkov, Ukraine
Mohammad Morshed Ayed Alsardia

Biology Research Institute of V. N. Karazin Kharkov National University, Kharkov, Ukraine
Andrew Anatolievich Bozhkov

Biology Research Institute of V. N. Karazin Kharkov National University, Kharkov, Ukraine

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APA Style

Natalia Igorevna Kurguzova, Anatoliy Ivanovich Bozhkov, Yuriy Viktorovich Nikitchenko, Mohammad Ali Yousef Al Begai, Anatoliy Vladimirovich Goltvyansky, et al. (2015). Interconnection of Antitoxic and Antioxidant Systems of the Organism under the Action of Natural Low Molecular Complex – Fungidol. American Journal of Biomedical and Life Sciences, 2(6-1), 25-32. https://doi.org/10.11648/j.ajbls.s.2014020601.15

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ACS Style

Natalia Igorevna Kurguzova; Anatoliy Ivanovich Bozhkov; Yuriy Viktorovich Nikitchenko; Mohammad Ali Yousef Al Begai; Anatoliy Vladimirovich Goltvyansky, et al. Interconnection of Antitoxic and Antioxidant Systems of the Organism under the Action of Natural Low Molecular Complex – Fungidol. Am. J. Biomed. Life Sci. 2015, 2(6-1), 25-32. doi: 10.11648/j.ajbls.s.2014020601.15

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AMA Style

Natalia Igorevna Kurguzova, Anatoliy Ivanovich Bozhkov, Yuriy Viktorovich Nikitchenko, Mohammad Ali Yousef Al Begai, Anatoliy Vladimirovich Goltvyansky, et al. Interconnection of Antitoxic and Antioxidant Systems of the Organism under the Action of Natural Low Molecular Complex – Fungidol. Am J Biomed Life Sci. 2015;2(6-1):25-32. doi: 10.11648/j.ajbls.s.2014020601.15

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@article{10.11648/j.ajbls.s.2014020601.15,
  author = {Natalia Igorevna Kurguzova and Anatoliy Ivanovich Bozhkov and Yuriy Viktorovich Nikitchenko and Mohammad Ali Yousef Al Begai and Anatoliy Vladimirovich Goltvyansky and Mohammad Morshed Ayed Alsardia and Andrew Anatolievich Bozhkov},
  title = {Interconnection of Antitoxic and Antioxidant Systems of the Organism under the Action of Natural Low Molecular Complex – Fungidol},
  journal = {American Journal of Biomedical and Life Sciences},
  volume = {2},
  number = {6-1},
  pages = {25-32},
  doi = {10.11648/j.ajbls.s.2014020601.15},
  url = {https://doi.org/10.11648/j.ajbls.s.2014020601.15},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajbls.s.2014020601.15},
  abstract = {The influence of the natural complex of low molecular weight compounds (fungidol) on antitoxic and antioxidant systems in animals was investigated. It was demonstrated that the introduction to the experimental animals of fungidol in doses a 0.05 ml per 100 g of body weight increases antioxidant enzymes activity in serum and liver, decreases the content of lipids hydroperoxides and other products of free radical reactions. The components of fungidol antioxidant activity correlated with the stability of membranes of erythrocytes in these animals. In the experimental model the toxic effect of copper sulfate was investigated. The increase in the activity of prooxidant system induced by fungidol correlated with its antitoxic effect.},
 year = {2015}
}

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TY  - JOUR
T1  - Interconnection of Antitoxic and Antioxidant Systems of the Organism under the Action of Natural Low Molecular Complex – Fungidol
AU  - Natalia Igorevna Kurguzova
AU  - Anatoliy Ivanovich Bozhkov
AU  - Yuriy Viktorovich Nikitchenko
AU  - Mohammad Ali Yousef Al Begai
AU  - Anatoliy Vladimirovich Goltvyansky
AU  - Mohammad Morshed Ayed Alsardia
AU  - Andrew Anatolievich Bozhkov
Y1  - 2015/01/23
PY  - 2015
N1  - https://doi.org/10.11648/j.ajbls.s.2014020601.15
DO  - 10.11648/j.ajbls.s.2014020601.15
T2  - American Journal of Biomedical and Life Sciences
JF  - American Journal of Biomedical and Life Sciences
JO  - American Journal of Biomedical and Life Sciences
SP  - 25
EP  - 32
PB  - Science Publishing Group
SN  - 2330-880X
UR  - https://doi.org/10.11648/j.ajbls.s.2014020601.15
AB  - The influence of the natural complex of low molecular weight compounds (fungidol) on antitoxic and antioxidant systems in animals was investigated. It was demonstrated that the introduction to the experimental animals of fungidol in doses a 0.05 ml per 100 g of body weight increases antioxidant enzymes activity in serum and liver, decreases the content of lipids hydroperoxides and other products of free radical reactions. The components of fungidol antioxidant activity correlated with the stability of membranes of erythrocytes in these animals. In the experimental model the toxic effect of copper sulfate was investigated. The increase in the activity of prooxidant system induced by fungidol correlated with its antitoxic effect.
VL  - 2
IS  - 6-1
ER  -

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