Hepatitis B and C Single and Co-Infection Patterns Among Emergency Patients in a Resource-Limited Setting

Fasakin Kolawole Asimiyu; Ajayi Oluwafemi David; Esan Ayodele Jacob; Omisakin Christopher Tope; Adams Olusegun Timothy; Ojiezeh Tony Ifeanyi; Aboderin Florence Ifechukwude

doi:doi:10.11648/j.ajbls.20150303.15

Hepatitis B and C Single and Co-Infection Patterns Among Emergency Patients in a Resource-Limited Setting

Fasakin Kolawole Asimiyu, Ajayi Oluwafemi David, Esan Ayodele Jacob, Omisakin Christopher Tope, Adams Olusegun Timothy, Ojiezeh Tony Ifeanyi, Aboderin Florence Ifechukwude

Published in American Journal of Biomedical and Life Sciences (Volume 3, Issue 3)

Received: 9 April 2015 Accepted: 18 April 2015 Published: 9 May 2015

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Abstract

Background: Hepatitis B and C viral infections continue to constitute major global health problems and are responsible for most liver related deaths. This study is carried out to reveal the hepatitis B and C single and co-infection patterns among emergency patients and their possible liver outcomes. Methods: Two hundred and eighty-eight (288) patients on initial visit from casualty unit were routinely screened for hepatitis B and C viruses over a period of two years in the haematology department. Diaspot one step enzyme immunoassay rapid kits for hepatitis B surface antigen (HBsAg) and anti-HCV respectively were used. HBsAg and anti-HCV seroprevalence and possible co-infections were evaluated using descriptive statistics of SPSS version 17 and expressed in mean and standard deviation, and male: female ratios. Results: Of the 288 research volunteers, 8.68% and 1.74% were positive for HBsAg and anti-HCV respectively. 1.04% was HBV and HCV co-infected. The overall mean age and male: female ratio were 44.4±17.3 years and 1.4:1 respectively. Lower mean age and higher male: female ratios were observed in HBV and HCV population. HCC remain the major liver outcome in HBV-infected and HBV/HCV co-infected research subjects. Conclusion: Hepatitis B and C viral infections still remain a major public health problem globally. There is need for continued aggressive advocacy on ‘Know your HBV and HCV status’ to reduce the scourge of these infections especially in rural and resource-limited settings where problem of poverty and ignorance have contributed to development of liver complications in these patients.

Published in	American Journal of Biomedical and Life Sciences (Volume 3, Issue 3)
DOI	10.11648/j.ajbls.20150303.15
Page(s)	55-60
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2015. Published by Science Publishing Group

Keywords

HBsAg, Anti-HCV, HCC, Seroprevalence, Male: Female Ratios, Gender Differences

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Fasakin Kolawole Asimiyu, Ajayi Oluwafemi David, Esan Ayodele Jacob, Omisakin Christopher Tope, Adams Olusegun Timothy, et al. (2015). Hepatitis B and C Single and Co-Infection Patterns Among Emergency Patients in a Resource-Limited Setting. American Journal of Biomedical and Life Sciences, 3(3), 55-60. https://doi.org/10.11648/j.ajbls.20150303.15

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ACS Style

Fasakin Kolawole Asimiyu; Ajayi Oluwafemi David; Esan Ayodele Jacob; Omisakin Christopher Tope; Adams Olusegun Timothy, et al. Hepatitis B and C Single and Co-Infection Patterns Among Emergency Patients in a Resource-Limited Setting. Am. J. Biomed. Life Sci. 2015, 3(3), 55-60. doi: 10.11648/j.ajbls.20150303.15

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AMA Style

Fasakin Kolawole Asimiyu, Ajayi Oluwafemi David, Esan Ayodele Jacob, Omisakin Christopher Tope, Adams Olusegun Timothy, et al. Hepatitis B and C Single and Co-Infection Patterns Among Emergency Patients in a Resource-Limited Setting. Am J Biomed Life Sci. 2015;3(3):55-60. doi: 10.11648/j.ajbls.20150303.15

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@article{10.11648/j.ajbls.20150303.15,
  author = {Fasakin Kolawole Asimiyu and Ajayi Oluwafemi David and Esan Ayodele Jacob and Omisakin Christopher Tope and Adams Olusegun Timothy and Ojiezeh Tony Ifeanyi and Aboderin Florence Ifechukwude},
  title = {Hepatitis B and C Single and Co-Infection Patterns Among Emergency Patients in a Resource-Limited Setting},
  journal = {American Journal of Biomedical and Life Sciences},
  volume = {3},
  number = {3},
  pages = {55-60},
  doi = {10.11648/j.ajbls.20150303.15},
  url = {https://doi.org/10.11648/j.ajbls.20150303.15},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajbls.20150303.15},
  abstract = {Background: Hepatitis B and C viral infections continue to constitute major global health problems and are responsible for most liver related deaths. This study is carried out to reveal the hepatitis B and C single and co-infection patterns among emergency patients and their possible liver outcomes. Methods: Two hundred and eighty-eight (288) patients on initial visit from casualty unit were routinely screened for hepatitis B and C viruses over a period of two years in the haematology department. Diaspot one step enzyme immunoassay rapid kits for hepatitis B surface antigen (HBsAg) and anti-HCV respectively were used. HBsAg and anti-HCV seroprevalence and possible co-infections were evaluated using descriptive statistics of SPSS version 17 and expressed in mean and standard deviation, and male: female ratios. Results: Of the 288 research volunteers, 8.68% and 1.74% were positive for HBsAg and anti-HCV respectively. 1.04% was HBV and HCV co-infected. The overall mean age and male: female ratio were 44.4±17.3 years and 1.4:1 respectively. Lower mean age and higher male: female ratios were observed in HBV and HCV population. HCC remain the major liver outcome in HBV-infected and HBV/HCV co-infected research subjects. Conclusion: Hepatitis B and C viral infections still remain a major public health problem globally. There is need for continued aggressive advocacy on ‘Know your HBV and HCV status’ to reduce the scourge of these infections especially in rural and resource-limited settings where problem of poverty and ignorance have contributed to development of liver complications in these patients.},
 year = {2015}
}

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TY - JOUR
T1 - Hepatitis B and C Single and Co-Infection Patterns Among Emergency Patients in a Resource-Limited Setting
AU - Fasakin Kolawole Asimiyu
AU - Ajayi Oluwafemi David
AU - Esan Ayodele Jacob
AU - Omisakin Christopher Tope
AU - Adams Olusegun Timothy
AU - Ojiezeh Tony Ifeanyi
AU - Aboderin Florence Ifechukwude
Y1 - 2015/05/09
PY - 2015
N1 - https://doi.org/10.11648/j.ajbls.20150303.15
DO - 10.11648/j.ajbls.20150303.15
T2 - American Journal of Biomedical and Life Sciences
JF - American Journal of Biomedical and Life Sciences
JO - American Journal of Biomedical and Life Sciences
SP - 55
EP - 60
PB - Science Publishing Group
SN - 2330-880X
UR - https://doi.org/10.11648/j.ajbls.20150303.15
AB - Background: Hepatitis B and C viral infections continue to constitute major global health problems and are responsible for most liver related deaths. This study is carried out to reveal the hepatitis B and C single and co-infection patterns among emergency patients and their possible liver outcomes. Methods: Two hundred and eighty-eight (288) patients on initial visit from casualty unit were routinely screened for hepatitis B and C viruses over a period of two years in the haematology department. Diaspot one step enzyme immunoassay rapid kits for hepatitis B surface antigen (HBsAg) and anti-HCV respectively were used. HBsAg and anti-HCV seroprevalence and possible co-infections were evaluated using descriptive statistics of SPSS version 17 and expressed in mean and standard deviation, and male: female ratios. Results: Of the 288 research volunteers, 8.68% and 1.74% were positive for HBsAg and anti-HCV respectively. 1.04% was HBV and HCV co-infected. The overall mean age and male: female ratio were 44.4±17.3 years and 1.4:1 respectively. Lower mean age and higher male: female ratios were observed in HBV and HCV population. HCC remain the major liver outcome in HBV-infected and HBV/HCV co-infected research subjects. Conclusion: Hepatitis B and C viral infections still remain a major public health problem globally. There is need for continued aggressive advocacy on ‘Know your HBV and HCV status’ to reduce the scourge of these infections especially in rural and resource-limited settings where problem of poverty and ignorance have contributed to development of liver complications in these patients.
VL - 3
IS - 3
ER -

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Author Information

Fasakin Kolawole Asimiyu

Department of Haematology, Federal Teaching Hospital, Ido Ekiti, Nigeria
Ajayi Oluwafemi David

Department of Pharmacology and Therapeutics, Afe Babalola University, Ado Ekiti, Nigeria
Esan Ayodele Jacob

Department of Haematology, Federal Teaching Hospital, Ido Ekiti, Nigeria
Omisakin Christopher Tope

Department of Haematology, Federal Teaching Hospital, Ido Ekiti, Nigeria
Adams Olusegun Timothy

Department of Family Medicine, Federal Teaching Hospital, Ido Ekiti, Nigeria
Ojiezeh Tony Ifeanyi

Department of Medical Laboratory Science, Afe Babalola University, Ado Ekiti, Nigeria
Aboderin Florence Ifechukwude

Department of Haematology and Immunology, College of Health Sciences, Obafemi Awolowo University, Ile Ife, Nigeria

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Fasakin Kolawole Asimiyu, Ajayi Oluwafemi David, Esan Ayodele Jacob, Omisakin Christopher Tope, Adams Olusegun Timothy, et al. (2015). Hepatitis B and C Single and Co-Infection Patterns Among Emergency Patients in a Resource-Limited Setting. American Journal of Biomedical and Life Sciences, 3(3), 55-60. https://doi.org/10.11648/j.ajbls.20150303.15

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Fasakin Kolawole Asimiyu; Ajayi Oluwafemi David; Esan Ayodele Jacob; Omisakin Christopher Tope; Adams Olusegun Timothy, et al. Hepatitis B and C Single and Co-Infection Patterns Among Emergency Patients in a Resource-Limited Setting. Am. J. Biomed. Life Sci. 2015, 3(3), 55-60. doi: 10.11648/j.ajbls.20150303.15

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AMA Style

Fasakin Kolawole Asimiyu, Ajayi Oluwafemi David, Esan Ayodele Jacob, Omisakin Christopher Tope, Adams Olusegun Timothy, et al. Hepatitis B and C Single and Co-Infection Patterns Among Emergency Patients in a Resource-Limited Setting. Am J Biomed Life Sci. 2015;3(3):55-60. doi: 10.11648/j.ajbls.20150303.15

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@article{10.11648/j.ajbls.20150303.15,
  author = {Fasakin Kolawole Asimiyu and Ajayi Oluwafemi David and Esan Ayodele Jacob and Omisakin Christopher Tope and Adams Olusegun Timothy and Ojiezeh Tony Ifeanyi and Aboderin Florence Ifechukwude},
  title = {Hepatitis B and C Single and Co-Infection Patterns Among Emergency Patients in a Resource-Limited Setting},
  journal = {American Journal of Biomedical and Life Sciences},
  volume = {3},
  number = {3},
  pages = {55-60},
  doi = {10.11648/j.ajbls.20150303.15},
  url = {https://doi.org/10.11648/j.ajbls.20150303.15},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajbls.20150303.15},
  abstract = {Background: Hepatitis B and C viral infections continue to constitute major global health problems and are responsible for most liver related deaths. This study is carried out to reveal the hepatitis B and C single and co-infection patterns among emergency patients and their possible liver outcomes. Methods: Two hundred and eighty-eight (288) patients on initial visit from casualty unit were routinely screened for hepatitis B and C viruses over a period of two years in the haematology department. Diaspot one step enzyme immunoassay rapid kits for hepatitis B surface antigen (HBsAg) and anti-HCV respectively were used. HBsAg and anti-HCV seroprevalence and possible co-infections were evaluated using descriptive statistics of SPSS version 17 and expressed in mean and standard deviation, and male: female ratios. Results: Of the 288 research volunteers, 8.68% and 1.74% were positive for HBsAg and anti-HCV respectively. 1.04% was HBV and HCV co-infected. The overall mean age and male: female ratio were 44.4±17.3 years and 1.4:1 respectively. Lower mean age and higher male: female ratios were observed in HBV and HCV population. HCC remain the major liver outcome in HBV-infected and HBV/HCV co-infected research subjects. Conclusion: Hepatitis B and C viral infections still remain a major public health problem globally. There is need for continued aggressive advocacy on ‘Know your HBV and HCV status’ to reduce the scourge of these infections especially in rural and resource-limited settings where problem of poverty and ignorance have contributed to development of liver complications in these patients.},
 year = {2015}
}

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