Objective Explore the correlation between anxiety disorder and serum 25-hydroxyvitamin D3 (25-(OH) D3) level in children, in order to guide the diagnosis and treatment of childhood anxiety disorders and to supply clinical measure. Method The experimental group was 124 children with anxiety disorders attending the Child Behavior and Development Clinic of Jingzhou Maternal and Child Health Hospital from January 2020 to December 2022, as the control group was 131 children who had health checkups in the same hospital during the meantime. The differences of serum 25-(OH) D3 levels between the two groups were compared. Children with anxiety disorder were further divided into 4 age groups according to each group with 2 years (24 months) apart: 11-12 years old (32 cases), 13-14 years old (38 cases), 15-16 years old (31 cases) and larger than 16 years old (23 cases). Then, the difference of 25-hydroxyvitamin D among 16 years old group (23 cases) was compared. Results The serum 25-(OH) D3 level of the experimental group was distinctively lower than that of the control group, [(18.25±7.68) ng/ml VS (28.63±9.52) ng/ml], P<0.05, with statistical difference; The rate of vitamin D lack and insufficiency was higher than that of the control group (89.52% VS 75.57%), P<0.05, with statistical difference; According to age group grouping, the vitamin D levels in the 15-16 year old and>16 year old groups were lower than those in the 11-12 year old and 13-14 year old groups, with statistically significant differences (P<0.05). Conclusion: Vitamin D deficiency is more common in children with anxiety disorders, and is more pronounced in children older than 15 years than in younger children.
| Published in | American Journal of Clinical and Experimental Medicine (Volume 12, Issue 1) |
| DOI | 10.11648/ajcem.20241201.11 |
| Page(s) | 1-4 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2024. Published by Science Publishing Group |
Anxiety Disorders, 25-hydroxyvitamin D3, Children
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APA Style
Huang, W., Wang, Z. (2024). Correlation Between Serum 25-hydroxyvitamin D3 Levels and Children with Anxiety Disorder. American Journal of Clinical and Experimental Medicine, 12(1), 1-4. https://doi.org/10.11648/ajcem.20241201.11
ACS Style
Huang, W.; Wang, Z. Correlation Between Serum 25-hydroxyvitamin D3 Levels and Children with Anxiety Disorder. Am. J. Clin. Exp. Med. 2024, 12(1), 1-4. doi: 10.11648/ajcem.20241201.11
AMA Style
Huang W, Wang Z. Correlation Between Serum 25-hydroxyvitamin D3 Levels and Children with Anxiety Disorder. Am J Clin Exp Med. 2024;12(1):1-4. doi: 10.11648/ajcem.20241201.11
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Download@article{10.11648/ajcem.20241201.11,
author = {Wenjuan Huang and Zhonghong Wang},
title = {Correlation Between Serum 25-hydroxyvitamin D3 Levels and Children with Anxiety Disorder},
journal = {American Journal of Clinical and Experimental Medicine},
volume = {12},
number = {1},
pages = {1-4},
doi = {10.11648/ajcem.20241201.11},
url = {https://doi.org/10.11648/ajcem.20241201.11},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.ajcem.20241201.11},
abstract = {Objective Explore the correlation between anxiety disorder and serum 25-hydroxyvitamin D3 (25-(OH) D3) level in children, in order to guide the diagnosis and treatment of childhood anxiety disorders and to supply clinical measure. Method The experimental group was 124 children with anxiety disorders attending the Child Behavior and Development Clinic of Jingzhou Maternal and Child Health Hospital from January 2020 to December 2022, as the control group was 131 children who had health checkups in the same hospital during the meantime. The differences of serum 25-(OH) D3 levels between the two groups were compared. Children with anxiety disorder were further divided into 4 age groups according to each group with 2 years (24 months) apart: 11-12 years old (32 cases), 13-14 years old (38 cases), 15-16 years old (31 cases) and larger than 16 years old (23 cases). Then, the difference of 25-hydroxyvitamin D among 16 years old group (23 cases) was compared. Results The serum 25-(OH) D3 level of the experimental group was distinctively lower than that of the control group, [(18.25±7.68) ng/ml VS (28.63±9.52) ng/ml], P16 year old groups were lower than those in the 11-12 year old and 13-14 year old groups, with statistically significant differences (P<0.05). Conclusion: Vitamin D deficiency is more common in children with anxiety disorders, and is more pronounced in children older than 15 years than in younger children.
},
year = {2024}
}
TY - JOUR T1 - Correlation Between Serum 25-hydroxyvitamin D3 Levels and Children with Anxiety Disorder AU - Wenjuan Huang AU - Zhonghong Wang Y1 - 2024/02/01 PY - 2024 N1 - https://doi.org/10.11648/ajcem.20241201.11 DO - 10.11648/ajcem.20241201.11 T2 - American Journal of Clinical and Experimental Medicine JF - American Journal of Clinical and Experimental Medicine JO - American Journal of Clinical and Experimental Medicine SP - 1 EP - 4 PB - Science Publishing Group SN - 2330-8133 UR - https://doi.org/10.11648/ajcem.20241201.11 AB - Objective Explore the correlation between anxiety disorder and serum 25-hydroxyvitamin D3 (25-(OH) D3) level in children, in order to guide the diagnosis and treatment of childhood anxiety disorders and to supply clinical measure. Method The experimental group was 124 children with anxiety disorders attending the Child Behavior and Development Clinic of Jingzhou Maternal and Child Health Hospital from January 2020 to December 2022, as the control group was 131 children who had health checkups in the same hospital during the meantime. The differences of serum 25-(OH) D3 levels between the two groups were compared. Children with anxiety disorder were further divided into 4 age groups according to each group with 2 years (24 months) apart: 11-12 years old (32 cases), 13-14 years old (38 cases), 15-16 years old (31 cases) and larger than 16 years old (23 cases). Then, the difference of 25-hydroxyvitamin D among 16 years old group (23 cases) was compared. Results The serum 25-(OH) D3 level of the experimental group was distinctively lower than that of the control group, [(18.25±7.68) ng/ml VS (28.63±9.52) ng/ml], P16 year old groups were lower than those in the 11-12 year old and 13-14 year old groups, with statistically significant differences (P<0.05). Conclusion: Vitamin D deficiency is more common in children with anxiety disorders, and is more pronounced in children older than 15 years than in younger children. VL - 12 IS - 1 ER -
Department of Pediatrics, The First Affiliated Hospital of Yangtze University, Jingzhou City, China
